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KMID : 0525720200250020093
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Journal of Chitin and Chitosan
2020 Volume.25 No. 2 p.93 ~ p.104
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Antiviral Activity of Chitosan, Chitin and Polysaccharides Derived From Seaweed
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Hwang Kwon-tack
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Abstract
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The corona virus is terrifying and fearing people all over the world. About 8 million people have been identified worldwide and about 400,000 have died, threatening human health since the Spanish flu in the early 20th century. To overcome COVID-19, no specific antiviral treatment or vaccine has been developed that can be used to control or suppress infection. More than 300 drugs are being developed for prophylactic and therapeutic purposes because the development of therapeutic agents is required before vaccine development, and many drugs are in clinical trials. In addition, vaccine development is actively underway to complete the end of COVID-19. In addition, major countries around the world, including Korea, are participating in vaccine development. On the other hand, the study of natural antiviral substances to improve safety by following the treatment of COVID-19 before the vaccine is developed is also of interest. In natural products with antiviral activity, propolis, Manuka honey, boswellia gem, myrrh and xylitol, and many essential oils and polyphenols are attracting attention. Along with this, marine polysaccharides such as carrageenan, alginic acid, fucan and chitosan are also of great interest. Chitosan, which is the central theme of this society, has been shown to be a hope for the complete overcoming of COVID-19 by exhibiting high binding and high antiviral effects with viruses due to its molecular properties and its characteristic transformation. Corona virus vaccines have been developed in the future and we hope that they will be used as a wide range of antiviral substances until we return to a safe routine.
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KEYWORD
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chitosan, antiviral effect, corona virus, vaccine, polysaccharides
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